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4.3 5つ星のうち4.3 298個の評価

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価格
新品 中古品
DVD 1枚組
¥3,128 ¥3,080
DVD 通常版
¥1,578
DVD 通常版
¥3,769
今すぐ観る レンタル 購入
フォーマット ワイドスクリーン, ドルビー, 色
コントリビュータ アンジー・ハーモン, ハリー・コニック・Jr, エイミー・マディガン, ポーラ・ケイル, ダン・アイアランド
言語 英語
稼働時間 1 時間 31 分

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商品の説明

【ストーリー】
デニスは乳がんの治療にすべてを捧げる医師。
彼は乳がん患者とその家族のためにいろいろなものを犠牲にしていた。
ある時は家族との団欒を犠牲にし、ある時は治療薬開発の資金を得るために奔走し多くの時間を乳がん治療の研究に時間を費やしていた。
その先にある乳がん患者の笑顔のために。

【特典】
★メイキング・ドキュメンタリー集(2種)
★予告編集

【スタッフ&キャスト】
《製作》 ニール・メロン、クレイグ・ゼイダン
《監督》 ダン・アイアランド
《脚本》 ヴィヴィエン・ラドコフ
《出演》 ハリー・コニック・Jr、ポーラ・ケイル、アンジー・ハーモン、エイミー・マディガン

【Copy Right】 (C)2008 Sony Pictures Television Inc. All Rights Reserved.

※ジャケット写真、商品仕様、映像特典などは予告なく変更となる場合がございますのでご了承ください。

登録情報

  • アスペクト比 ‏ : ‎ 1.78:1
  • メーカーにより製造中止になりました ‏ : ‎ いいえ
  • 言語 ‏ : ‎ 英語
  • 梱包サイズ ‏ : ‎ 18.03 x 13.76 x 1.48 cm; 83.16 g
  • EAN ‏ : ‎ 4547462059307
  • 監督 ‏ : ‎ ダン・アイアランド
  • メディア形式 ‏ : ‎ ワイドスクリーン, ドルビー, 色
  • 時間 ‏ : ‎ 1 時間 31 分
  • 発売日 ‏ : ‎ 2009/9/2
  • 出演 ‏ : ‎ エイミー・マディガン, ハリー・コニック・Jr, アンジー・ハーモン, ポーラ・ケイル
  • 字幕: ‏ : ‎ 日本語, 英語
  • 販売元 ‏ : ‎ ソニー・ピクチャーズエンタテインメント
  • ASIN ‏ : ‎ B002DKMS2I
  • ディスク枚数 ‏ : ‎ 1
  • カスタマーレビュー:
    4.3 5つ星のうち4.3 298個の評価

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星5つ中4.3つ
5つのうち4.3つ
298グローバルレーティング

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他のお客様にも意見を伝えましょう

上位レビュー、対象国: 日本

2023年2月8日に日本でレビュー済み
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涙無くしては見ることができませんでした。素晴らしい映画です。
1人のお客様がこれが役に立ったと考えています
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2022年12月22日に日本でレビュー済み
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乳がんの世界を劇的に変えたお医者様のお話です。狭い研究室で始まった乳がんの新薬の研究。資金を集めたり、薬が認められなかったり、治験に参加する患者や家族の思いが赤裸々につづられています。何度も涙し、こんなお医者様がいらっしゃることに胸が熱くなりました。
1人のお客様がこれが役に立ったと考えています
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2022年5月24日に日本でレビュー済み
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感動して涙が止まらなかったが吹き替え版もあればいいのに
1人のお客様がこれが役に立ったと考えています
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2020年5月22日に日本でレビュー済み
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乳がんHER2の新薬の研究から認可がおりるまでの道のりの厳しさ。 医師の苦悩も描かれており。乳がんと診断されての治療や再発した時の患者の思い、医師と家族、患者と患者の恋愛や支えている家族の思いも同時に描かれている。全てを描くのは難しいが、よくできている映画だと思います。
1人のお客様がこれが役に立ったと考えています
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2018年11月24日に日本でレビュー済み
Amazonで購入
内容に引き込まれました。主役の本職がジャズシンガー&ピアニストなんて信じられないほど適役です。他のキャスティング、脚本も素晴らしいです。
2人のお客様がこれが役に立ったと考えています
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2013年11月6日に日本でレビュー済み
Amazonで購入
安いお値段で購入させていただきましたが、本当に素晴らしいドラマで
感動で・・・涙・・涙・・・でした!
4人のお客様がこれが役に立ったと考えています
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2017年9月3日に日本でレビュー済み
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1980年代の古い映画だが、2017年の今観ても楽しめる作品。ガンに対して真摯に向き合っている研究者の様子がわかり、それが現代医学になお生きている事がありがたく感じた。
4人のお客様がこれが役に立ったと考えています
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2023年3月28日に日本でレビュー済み
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この手の作品はディテールを大事にしなければいけないと思います。見ていて残念ながら、登場人物に感情移入が出来ずに終わりました。いらないシーンが多すぎました。

他の国からのトップレビュー

すべてのレビューを日本語に翻訳
Helen Ali
5つ星のうち5.0 I love this movie
2019年11月8日にカナダでレビュー済み
Amazonで購入
very good, kind of tearjerking.
Helen O'neill
5つ星のうち5.0 LIVING PROOF
2018年11月30日にオーストラリアでレビュー済み
Amazonで購入
There is nothing I can say but thank you, the DVD arrived before the estimated time, was a good quality DVD and the movie was fabulous. Thank you for making this available for me.
Konstanz
5つ星のうち5.0 A good dramatization of the book.
2013年3月16日にカナダでレビュー済み
Amazonで購入
Must see for anyone reading the book, and/or anyone dealing with Her2 positive breast cancer. Thank god for Revlon stepping in to fund this research thats saved so many women's lives.
Tom Brody
5つ星のうち5.0 A first rate account of the financial, regulatory, and emotional burdens of drug-development.
2010年11月12日にアメリカ合衆国でレビュー済み
Amazonで購入
LIVING PROOF is a biographical account of Dr. Dennis Slamon's discovery and invention of a new class of oncology drugs and, in particular, trastuzumab (HER-2). Trastuzumab is an antibody used for curing breast cancer. First, let us look at the regulatory aspects of this film. Then, let us look at the emotional aspects of the movie.

REGULATORY ASPECTS. The viewer will learn about inclusion criteria for a clinical trial. We learn that a subject must have breast cancer, and that the tumor cells must be HER2 positive. We learn that the goal of Phase I trials is to characterize safety ("side-effects"). We also learn about exclusion criteria from this movie, for example, the exclusion criterion of the study subject having had too many rounds of prior chemotherapy. This movie shows one of the characters being refused entry into the Phase II trial because she failed to satisfy this particular criterion. Also, we learn that funding for any particular clinical trial can be a start-and-stop activity. In this movie, we learn that where GENENTECH decided not to fund the study, another company, REVLON stepped in and provided money. Another take-home lesson, is that clinical trials require regulatory approval from the FDA, and that clinical trials need to be designed by physicians who actually have experience in trial design (just because you are a doctor who discovers a new drug does not mean that you have the slightest clue in trial design). The movie shows Dr. Shamon being told that "his" clinical trial will be taken over by physicians who actually have experience in trial design. Also, relating to concept of regulatory approval, we see a cancer victim who had been approved for entry into a Phase III trial, begging a receptionist to be given drug right away, "I only have a day to live, I need the drug right now, I can't wait until next week." We learn of the concept "quality of life," which is an issue for most clinical trials for chronic, debilitating diseases. Quality of life in these clinical trials is always measured by a special questionnaire called, "Health Related Quality of Life instrument." LIVING PROOF teaches us all of these lessons. These lessons, as taught by LIVING PROOF, can be understood by children of the ages 8-12, by teenagers, and by adults.

EMOTIONAL ASPECTS. To cut to the chase, this movie requires a collection of Kleenex tissues or handkerchiefs. We see various examples of emotional dispair, where is woman is being denied entry into a clinical trial, because she does not meet the entry criteria (inclusion criteria). The result is that she dies leaving behind a family and children (Kleenex #1). Another character turns down a marriage proposal, because she believes that she will eventually die of her breast cancer (Kleenex #2). There are other scenes of emotional triumph, which also require the handkerchief. One of the characters has reached the point of despair, and decides to live out her final days in Mexico, sipping margueritas on a relaxing beach, instead of vomiting from chemotherapy. But then, she gets persuaded to enter Dr. Slamon's trial, and at the end of the movie, she is declared totally cancer-free (Kleenex #3, #4, and #5).

THE BAD GUY. One unusually interesting theme in this story concerns an employee at Genentech known as "Reinhart." He is portrayed as the bad guy in this movie, apparently because of his expertise in trial design, in contrast to Dr. Slamon's lack of expertise in this skill. Even though it is not certain why "Reinhard" is the bad guy, any viewer of this movie will sense that something good has occurred when Reinhard is taken off of the trial. While I do not know if "Reinhard" corresponds to a real person, it is often the case that, in management, people with Reinhard-like characteristics are encountered. This particular Reinhard had characteristics that were both good and bad.

SUMMARY. The movie sticks to events relating to the various phases of this drug -- research, funding, regulatory approval, enrollment, adverse drug reactions ("side effects"), trouble getting enough patients enrolled, and efficacy. The movie does disclose some of the outside activities of all the characters, for example, a courtship between an African-American woman and a Caucasian man (happy ending), Christmas party not attended by dead mother, and fact that Dr.Slamon did not have time to be a devoted "family man," that is, to attend school functions of his daughter. But these outside activities merely act as a cementing substance to the "bricks" of this movie, namely, the steps required to get regulatory approval. The movie emphasizes the issue of femininity, for example, where the soundtrack plays Dionne Warwick's, "I SAY A LITTLE PRAYER," at which point the film dwells on each cancer victim, that is, on her activities in grooming, lipstick, womanly shoes, skirts, and so on.

CRITICISM. I only have one critisism. The movie does not mention that Phase II trials and Phase III trials are usually randomized (placebo versus study drug). However, it is quite possible that the HERCEPTIN clinical trials only contained one arm (study drug only). But it is also possible that the movie failed to mention randomization, in order not to scare away the viewers of this movie (to scare them away from participating in clinical trials). FIVE STARS for LIVING PROOF.
10人のお客様がこれが役に立ったと考えています
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Loves To Read
5つ星のうち5.0 LIVING PROOF OF FAITH AND PERSEVERANCE!!
2009年12月26日にアメリカ合衆国でレビュー済み
Amazonで購入
This made for TV movie is based on the book, HER-2, which is the story of Dr. Dennis Slamon's passionate pursuit of a cure for breast cancer. It is essentially the battle between Slamon and Genentech, the company that owns the rights to Herceptin. Slamon is the lead research doctor on the drug and believes with all his being that it can give new life to at least 40,000 of the 200,000 new breast cancer cases each year. Genentech does not believe it has the potential to be financially successful, which is their definition of a successful drug (at least how it is pictured in the film). At a point in the development of the drug, Hollywood friends come to the rescue and raise the money to keep the project going. It is clearly Slamon's drive and passion that is keeping the research alive. It is also the general story of what it takes to bring a new drug to market through the FDA approval process-no insignificant task no matter how great your drug is. The film becomes very emotional as he finally wins approval to begin testing on women in stage IV breast cancer-those that are considered without hope from any approved treatments. Because of the extremely tight restrictions put in place by Genentech, he must exclude some women who are desperate for any hope of a cure. Even more heart wrenching are those who are helped in the Phase I testing but are not allowed to move to Phase II because of the Genentech restrictions. He also discovers that it helps some but not others which is powerfully visualized in a scene where the treatment room is shown full of the test patients that started and one by one those who have died disappear. The film is a testimony to the belief and perseverance of one man who was determined to make a difference against great odds. Where might that apply in our lives? While the drug is not without controversy today, it has saved thousands of lives and fulfilled Slamon's dream of making a difference in the battle against breast cancer. The one shortcoming in the movie is the depiction of Genentech as, more or less, the evil enemy of this dedicated doctor (which they may very well have been) but there is another side to every drug story. And that is that there are hundreds (maybe thousands) of potential drugs out there to cure all kinds of diseases and some are worthwhile and some are not. There is not enough money to find out if they all work and someone has to make the decisions of which ones to pursue and they all sound great in the development stage. Making those kind of life and death decisions requires the wisdom of Solomon, something very few people have. These decisions will only get more difficult as our population ages and the money shrinks to provide treatment for everyone for every disease. This is a wonderful, inspirational film worth watching.
6人のお客様がこれが役に立ったと考えています
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