Without evidence

Sarah Boseley “Little evidence that light drinking in pregnancy is harmful, say experts” https://www.theguardian.com/society/2017/sep/11/little-evidence-that-light-drinking-alcohol-in-pregnancy-is-harmful-say-experts


英国のNHSが昨年制定した新しいガイドラインでは、妊娠中の女性に対して完全な禁酒を勧告している。しかし、妊娠中にアルコールを全く摂取しない人は実は少ない。勿論過剰な飲酒が胎児に悪影響を及ぼす事に関しては強いエヴィデンスが蓄積されている。しかし、ブリストル大学の研究者たちによる最新の研究によれば、完全な禁酒とちょっとの飲酒の間には、胎児への影響ということに関しては明確な差はないようである。


“Despite the distinction between light drinking and abstinence being the point of most tension and confusion for health professionals and pregnant women and contributing to inconsistent guidance and advice now and in the past, our extensive review shows that this specific question is not being researched thoroughly enough, if at all,” they write in the BMJ Open journal.

Without the evidence, it is impossible to say whether drinking small amounts is safe or not, they say. “Formulating guidance on the basis of the current evidence is challenging,” they say. They agree that drinking no alcohol in pregnancy is the safest option, but women should be told that little research has been done on light drinking, although they should also be informed that “absence of evidence is not evidence of absence,” they write.

研究に対する反応;

A number of experts said women who had been alarmed by the NHS abstinence guidance would be relieved. “This valuable and humane study has shown that warnings about the dangers of drinking any alcohol at all during pregnancy are not justified by evidence,” said David Spiegelhalter, Winton professor for the public understanding of risk at the University of Cambridge*1.

“A precautionary approach is still reasonable, but with luck this should dispel any guilt and anxiety felt by women who have an occasional glass of wine while they are pregnant.”

Dr Christoph Lees, clinical reader in obstetrics at Imperial College London*2, said the study showed how the weakness of the evidence behind the official guidance. “Whilst it is possible that light drinking is associated with a slightly higher risk of having a small baby, there are other possible explanations. It will be an important challenge for those responsible for pubic health messages to convey nuanced advice that explains how robust or otherwise the evidence is,” he said.

また、

Professor Russell Viner*3 from the Royal College of Paediatrics and Child Health took a different perspective on the same study, however. “This research confirms that based on current evidence it is impossible to say what constitutes a ‘safe’ amount of alcohol a woman can drink if she’s trying for a baby and for women who are pregnant.

“My advice to women is that it’s best not to drink at all if you’re trying for a baby or pregnant. Regularly drinking even small amounts could be harmful and should be avoided, in line with the precautionary approach.”